Rapid development and scale-up of drug delivery nanoparticles using a microfluidic platform
28th and 29th June 2018
Microfluidic devices have been broadly used to produce nanoparticles for genetic medicine, vaccines, and drug delivery systems for small molecules, proteins, and peptides. Compared to conventional methods, microfluidic production offers superior control, reproducibility and scalability of the nanoparticle production process that promises to overcome significant challenges in the translation of these therapeutics: Fine control of process parameters afforded by microfluidics, allows optimisation of nanoparticle quality and encapsulation efficiency. Automation improves the reproducibility and optimisation of formulations. Furthermore, the continuous nature of the microfluidic process is inherently scalable, allowing optimisation at low volumes to conserve scarce or costly materials, and seamless scale-up of optimised formulations by employing multiple microfluidic mixers performing identical unit operations in parallel.
This talk, presented at the University of Melbourne on 28th June and at the University of Queensland on 29th June, focused on examples from literature and highlighted how users of this technology are revolutionising medicine. Original data was presented to demonstrate how the technology has been used to accelerate all stages of nanomedicine development from discovery to manufacturing. Download flier
If you missed the seminar and would like an onsite demonstration please contact us.