RedShiftBio HaLCon

RedShift Bio HaLCon Protein Analyser is designed specifically to provide quick, easy, and accurate protein titer measurements for biopharmaceutical development and manufacturing.

RedShiftBio HaLCon

RedShift Bio HaLCon Protein Analyser is designed specifically to provide quick, easy, and accurate protein titer measurements for biopharmaceutical development and manufacturing.

Manufacturer RedShiftBio
Product Series HaLCon
Measurement principle Liquid chromatography system
Application Protein Interactions & Binding Affinity
Sample type IgG (all subtypes)
Dynamic Range0.1 g/L – 10 g/L
Analysis Time < 5 minutes
Reagent Capacity 1,000 analyses

Product Overview

The RedShift HaLCon is a purpose-built liquid chromatography system that provides on-demand, real-time protein titer measurements for bioprocessing. It offers results equivalent to traditional protein A, HPLC with a faster, easier, and more cost-effective platform method.

Using a compact, space-saving design, HaLCon works by performing a proprietary trap-and-elute technique to quantify the amount of IgG in a cell-free sample.

HaLCon integrates seamlessly into any bioprocessing suite without disrupting existing workflows or equipment and requires no chromatography expertise. Users can obtain an equivalent protein titer measurement in under five minutes right at the point of need, allowing far more efficient use of bioprocess reactors and freeing up valuable HPLCs and highly trained analysts to run more complex experiments.

  • Demonstration video
  • Benefits
  • Applications

Demonstration video

Benefits

  • Protein titre LC technology correlates closely with gold-standard HPLC measurement
  • Easy-to-use, streamlined operation requiring minimal user training
  • No chromatography expertise required
  • Individual sample or automated sampling
  • Real time data, Sample-to-answer in just five minutes
  • Compact design with convenient plug-and-play consumables
  • Sample flow path is completely contained

Applications

Real-Time Protein Titre Measurements for Bioprocessing

UPSTREAM: Monitor bioreactor product yield and quickly identify productive cell lines. Change of reject process based on real time data.

HARVEST: Routine monitoring with daily or more frequent measurements help to minimise hold times due to product uncertainty. Harvest on time.

DOWNSTREAM: Earlier preparation of purification columns.

 

Product Enquiry

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