NanoAssemblr Benchtop

NanoAssemblr Benchtop is capable of manufacturing nanoparticle volumes between 1 to 20 mL per batch, which is ideal for low-cost formulation and process development.

NanoAssemblr Benchtop

NanoAssemblr Benchtop is capable of manufacturing nanoparticle volumes between 1 to 20 mL per batch, which is ideal for low-cost formulation and process development.

Manufacturer Precision Nanosystems
Product SeriesNanoAssemblr platform
Measurement principleEmulsion and Liposome Processing
ApplicationNanoparticle formulation
Temperture control20 - 70°C (with heating block accessory)
Formulation volume1 to 20 mL per batch

Product Overview

The NanoAssemblr Benchtop is a nano particle synthesis system that enables the rapid, reproducible, and scalable manufacture of next generation nano particle formulations for the targeted delivery of therapeutic and diagnostic agents to cells and tissues. It is particularly designed for novel nano particles that would be difficult to make with alternative manufacturing methods.

The NanoAssemblr Benchtop is capable of manufacturing nanoparticle volumes between 1 to 20 mL per batch, which is ideal for low-cost formulation and process development. The quick and precise manufacture of nano-medicines allows for 30+ formulations in a day. Users can control size by process and composition – even tweak process parameters such as mixing ratios, flow rate and lipid composition in order to fine tune size (~20 to 120+nm).

The system uses proprietary microfluidics technology to support the controlled, bottom-up, molecular self-assembly of nanoparticles through millisecond mixing (<3ms) of components at the nanolitre scale (<20nL). 

  • Benefits
  • Applications
  • Accessories

Benefits

Particle Size Control: Combining reproducible microfluidics with precise fluid injection allows users to efficiently find and dial-in the optimal conditions for nanoparticle formation.

Efficient Drug Loading: Improved drug loading or encapsulation efficiency compared to conventional methods.

Scalable Production: The continuous flow microfluidic process can be scaled up by increasing total volume injected through a single mixer, or by employing multiple mixer in parallel without affecting the underlying conditions of nano particle synthesis. This allows formulations to be optimised at bench scales, and scaled up with little to no re-optimisation at each change in batch size.

Versatile: Suitable for creating a variety of different particles including:
• Biodegradable polymer nanoparticles (ex: PLGA)
• Amphiphilic block co-polymer micelles (ex: PEG-PLA)
• Dendrimer nanoparticles
• Polymer-drug conjugates
• Nucleic acid Lipid Nanoparticles (LNP)
• Lipsomes, Emulsions, Organic/ Inorganic Nanoparticles

Applications

Gene delivery via high in vivo cell transfection efficiency
Nanoparticle design
Drug development
Lipid nanoparticles formulation
Liposome encapsulation
Polymeric nanoparticles

Accessories

NanoAssemblr Benchtop Cartridges

Precision Nanosystems Used with the Benchtop Instrument, these disposable cartridges allow for the synthesis of a variety of nanoparticles (liposomes, polymeric nanoparticles, lipid nanoparticles). They have a broad solvent compatibility and can be used to make nanoparticles via nanoprecipitation.  Size and properties of the nanoparticles can be altered through the flow rate at which formulation materials are pumped through the cartridge.

Benefits of the Microfluidic cartridge include:
• Isolated fluid path prevents cross-contamination
• Laminar flow and time-invariant mixing
• Rapid mixing (<3 ms)
• Nanoliter reaction volumes (<20 nL)
• <2 min per formulation, 30+ formulations per day

Product Enquiry

To enquire about this product, please send through your details below and one of our product specialists will be in touch to discuss your requirements

Required field*

We value your privacy and will not sell or share the details you provide with any other organisation