Celena | ATA Scientific

The CELENA S is a compact, easy-to-use digital imaging system that enables multicolour fluorescence imaging, live-cell imaging, z-stacking and automated cell counting.

Manufacturer	Logos Biosystems
Product Series	CELENA
Measurement principle	Microscopy – Cell image analysis
Application	Live cell image analysis
Imaging modes	Epifluorescence and transmitted light (brightfield and phase contrast)
Stage	Mechanical X/Y stage, motorised Z stage; accommodates an onstage incubator

The CELENA S is a compact, easy-to-use digital imaging system that captures multicolour fluorescence images, brightfield images and phase-contrast images.

An onstage incubation system gives precise control over temperature, humidity, and gases for live cell monitoring. High-quality images are captured using precision optics that include a highly sensitive CMOS sensor and digitally controlled LED light sources with hard-coated fluorescence filters that are highly sensitive to even the faintest of fluorescence signals. Interchangeable objectives, filter cubes and vessel holders serve a wide range of imaging needs.

User-friendly and powerful data analysis software makes it easy to acquire and analyse multicolour fluorescence, brightfield, Z-stack and time-lapse images as well as monitor cell growth, cell count, concentration and viability.

All-in-one compact imaging system with onboard computer
Capture, overlay, edit and save images with the simple user interface. Advanced optics and adjustable transmitted light allow for high-quality brightfield, multicolour fluorescence and phase-contrast imaging. Automated cell counting provides quick, accurate and reliable cell count and viability measurements.

High-quality precision optics and low maintenance costs
Interchangeable LED filter cubes allow precise control with powerful and uniform illumination. LEDs have a long lifetime of 50,000+ hours.

Sophisticated image analysis software
Choose from a variety of measurement and annotation tools to analyse your images immediately upon capture. Monitor live cells with the time-lapse function, cell counter or growth monitor and capture multiple images along the z-axis using the z-stack function.

Apoptosis
Autophagy
Cell Cycle
Cell growth/Proliferation
Cell counting
Cell viability/toxicity
Cell migration
Cell morphology
Co-localisation
Confluency
Cytotoxicity
Drug discovery
Histology
Immunofluorescence
NF-kB translocation
Organoid/spheroid morphology
Transfection efficiency

What is the CELENA S Automated Imaging System?
The CELENA S is a compact automated fluorescence imaging system designed for rapid cell imaging, analysis, and documentation. It combines brightfield and fluorescence microscopy with intuitive software for routine laboratory workflows.

What applications is the CELENA S commonly used for?
The system is ideal for cell culture monitoring, fluorescent protein expression studies, transfection efficiency assessment, cell viability analysis, immunofluorescence imaging, and general biological research.

What fluorescence channels are available?
CELENA S supports multiple fluorescence channels, allowing users to image common fluorophores such as DAPI, FITC/GFP, TRITC/RFP, and Cy5, depending on the filter configuration installed.

Can the CELENA S perform automated image acquisition?
Yes. The system offers automated image capture, multi-channel imaging, Z-stack acquisition, and time-lapse imaging to improve workflow efficiency and reproducibility.

Does the CELENA S include image analysis software?
Yes. Integrated software enables image acquisition, fluorescence quantification, cell counting, area measurements, and image enhancement without requiring additional software packages.

Can live cells be imaged with the CELENA S?
Yes. The system is suitable for both live-cell and fixed-cell imaging. Optional environmental control accessories can support extended live-cell experiments.

What sample formats can be used?
CELENA S accommodates a variety of sample formats, including microscope slides, culture dishes, flasks, chamber slides, and multi-well plates.

Is the CELENA S suitable for high-throughput screening?
The system can automate imaging across multi-well plates, making it suitable for small- to medium-scale screening applications and routine fluorescence imaging workflows. CELENA X is a true high-content screening (HCS/HCA) platform designed for automated quantitative analysis of large numbers of samples.

How easy is the system to use?
The CELENA S features an intuitive touchscreen interface and user-friendly software, allowing researchers to acquire high-quality images with minimal training.

What are the advantages of CELENA S compared with a conventional fluorescence microscope?
CELENA S provides automated imaging, standardised acquisition settings, digital image management, and integrated analysis tools, helping improve reproducibility while reducing operator variability and imaging time.

Can I have a demonstration or free trial of the CELENA?
Yes, if a system is available. Contact us for a booking. We can arrange a personalised demo and test your samples within our lab facility in Sydney. Onsite free trials are also available. Contact us or complete a request a demo form to get started.

Automated high content cell imaging and analysis with multicolour fluorescence for drug discovery and cell biology

Manufacturer	Logos Biosystems
Product Series	CELENA
Measurement principle	Microscopy – Cell image analysis
Application	Live cell image analysis
Imaging modes	4-channel fluorescence, brightfield, phase contrast, colour brightfield
Camera	Monochrome and colour CMOS
Stage	Motorised XYZ stage
Autofocus	Laser Autofocus

The CELENA-X is is a fully automated digital imaging system that makes it easy to set up a time lapse imaging sequence for lengthy cell-based assays. This fully integrated system with onstage incubator allows users to quickly and easily set up high-content imaging experiments to measure phenotypes of interest objectively, quantitatively and reproducibly within a precisely controlled environment.

The CELENA X can be customised with a range of interchangeable LED filter cubes, high quality dual cameras and various objectives to meet event the most demanding of cell imaging needs.

Customised workflows can be created that will automatically focus in on and capture each specified field in each specified well with the preset imaging conditions. Live cells can be monitored with the time lapse function or the growth monitor to produce high content time lapse images and videos.

LASER AUTOFOCUS

Rapid and reproducible focusing
Minimised photoxicity and photobleaching

FULLY AUTOMATED PLATE AND SLIDE IMAGING

Ideal for kinetic live cell assays, fixed cell assays and slide scanning
Motorized XYZ stage, filter cube stage, and objective turret

LIVE CELL ASSAY SUPPORT

Onstage incubation system for a variety of experiments in physiological and non-physiological conditions

FOUR IMAGING MODES

Fluorescence imaging in four channels, brightfield, color brightfield, and phase contrast imaging
Z-stack and time lapse capabilities
Interchangeable filter cubes and objectives (Olympus and Zeiss compatible)

POWERFUL, EASY-TO-USE USER INTERFACE

Simple setup of imaging protocols
Seamless integration of imaging and data analysis processes

CUSTOMISABLE HIGH CONTENT ANALYSIS

Create and customise image analysis projects
Quantitatively analyse multiple image-based phenotypes

What is the CELENA X and what does it do?

The CELENA X is a fully automated high-content imaging system designed for rapid, quantitative cell imaging and analysis. It performs automated plate and slide scanning with four-channel fluorescence, brightfield, phase contrast, and colour brightfield imaging modes. It is used in drug discovery and cell biology to measure cellular phenotypes objectively and reproducibly across multi-well plates (6 to 1536 wells), slides, petri dishes, and culture flasks.

What fluorescence channels and filter cubes are available on the CELENA X?

The CELENA X supports four-channel fluorescence imaging using interchangeable LED filter cubes with a 50,000+ hour lifespan and adjustable intensity. Available filter cubes include DAPI, EGFP, RFP, mCherry, ECFP, EYFP, DSRed, Cy5, Cy7, Cy3/TRITC Long Pass, GFP Long Pass, and Cy5 Long Pass, plus custom filter options. The system is compatible with Olympus, Zeiss, and Logos Biosystems objectives across a magnification range of 1.25x to 100x.

How does the CELENA X autofocus system work and why does it matter for live-cell imaging?

The CELENA X offers both standard image-based autofocus and an optional laser autofocus module. The laser autofocus provides rapid and reproducible focusing while minimising phototoxicity and photobleaching — critical considerations for time-lapse live-cell experiments. The motorised XYZ stage (120 mm x 80 mm X/Y, 10 mm Z travel) combined with the laser autofocus enables consistent focus across large multi-well plates.

Can the CELENA X maintain physiological conditions during live-cell imaging?

Yes. The CELENA X supports optional CX Stage Top Incubators (Basic and Pro models) that provide temperature control, CO₂, and CO₂/O₂ gas supply for maintaining physiological or custom environmental conditions during imaging. This enables long-duration time-lapse experiments, kinetic assays, and other live-cell studies requiring precise environmental control without removing cells from the microscope stage.

What analysis capabilities does the CELENA X software provide?

The CELENA X includes two software components: CELENA X Explorer for protocol setup and seamless integration of imaging and data analysis, and CELENA X Cell Analyser for creating customisable analysis pipelines. Users can identify cellular and subcellular objects, process images for optimal data collection, and perform quantitative measurements. Pipelines can be saved and reused, supporting batch processing from simple fixed-cell assays to complex time-lapse live-cell experiments.

What cell biology assays can be run on the CELENA X?

The CELENA X supports multiple documented application workflows including cell counting, cytotoxicity (brightfield and fluorescence), transfection efficiency, wound healing, apoptosis, confluency monitoring, calcium signaling, phagocytosis, cell cycle analysis, image stitching, and 3D cell model imaging (organoids and spheroids). Both fixed-cell and kinetic live-cell assay formats are supported.

Can I have a demonstration or free trial of the CELENA X?

Yes, if a system is available. Contact us for a booking. We can arrange a personalised demo and test your samples within our lab facility in Sydney. Onsite free trials are also available. Contact us or complete a request a demo form to get started.

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