Fast, label-free techniques for assessing biomolecular stability and efficacy of gene therapies and vaccines
09 Aug, 2021 | Newsletters
|In this newsletter we highlight the latest analytical tools from Malvern Panalytical to help produce safe, reliable, high quality products and accelerate discovery through to manufacturing and process control. |
Size-exclusion Chromatography (SEC), together with compositional analysis, can determine concentration and molecular weight of two distinct components. Differential scanning calorimetry (DSC) on the other hand, is a fundamental tool for characterising proteins and plays a key role in understanding thermal and conformational stability. Learn in detail how these 2 techniques play a crucial role in your development processes.
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Using SEC and DSC to optimise loading time and stability of Virally Vectored therapies and vaccines.
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Using MADLS and NTA for quick, label-free measurements of rAAV aggregation, capsid charge, and particle concentration.
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Comprehensive overview of rapid, label-free characterisation methods using DLS, DSC, NTA, SEC.
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