Develop and manufacture mRNA vaccines in Australia
16 Mar, 2021 | Newsletters
|RACI Pharm Group in collaboration with ATA Scientific hosted a webinar on 24th February 2021:|
Identification of a Novel LNP Delivery System for a COVID-19 Self-amplifying mRNA Vaccine and Enabling Rapid Development using Microfluidics
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Abstract: RNA vaccines are a relatively recent innovation but are at the forefront of the many vaccine technologies providing solutions for the COVID-19 pandemic. This talk shows how PNI have identified a potent LNP delivery system for self-amplifying and how this is now been applied to COVID-19 mRNA vaccines.
In addition, it describes why the NanoAssemblr® GMP System is being used by many companies to provide accelerated clinical and commercial development of COVID-19 nanomedicines, by reducing the number of engineering batches through seamless transfer of manufacturing process: by eliminating cleaning validation by using a fully disposable single use fluid path; by supporting all stages of clinical development through a modular continuous flow pumping system capable of producing volumes of 200 mL to >100 L at outputs up to 12 L/h; and, by enabling flexibility and redundancy in clinical development plans through simple tech transfer of the GMP System to any global non-GMP and GMP facility.
Presenter: Dr Andrew Geall, CEO RNA Consulting, LLC and Chief Scientific Officer of Precision NanoSystems Inc. (PNI), based in Vancouver, Canada. Andrew and PNI is focused on the creation and commercial development of transformative nanoparticle medicines with its partners using their proprietary LNP delivery systems and microfluidic formulation platform, current cutting edge technology. Andrew has enjoyed a most distinguished career in vaccine technologies in senior positions within therapeutic goods organisations. Further details can be found at https://www.linkedin.com/in/andy-geall-116a9624
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Demonstration videos showing mRNA vaccine development: From formulation to manufacture
Nanoassemblr Ignite mRNA Vaccine Demo. The Ignite with NxGen Technology is the go-to for nanomedicine development for over 200 biopharma companies, bringing the latest innovations developed for the cGMP system to the bench — saving time and money.
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PNI’s Microfluidic Platform is a Leap Forward in Manufacturing
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