Extreme liquid chromatography
Jasco X-LC extreme high pressure HPLC
The Jasco X-LC® extreme high pressure liquid chromatography systems are capable of delivering solvents at pressures up to 15,000 psi. These pressures coupled with very small particle size columns allow the user to achieve chromatographic speed, sensitivity and efficiency far beyond traditional HPLC.
Now you can have both HPLC and X-LC in a single system. Run existing 3 to 5 µm column technology at flow rates up to 5 mL/min at conventional pressures or operate with X-LC columns (particle sizes down to 1.5 µm), with flow rates up to 3.5mL/min at 15,000 psi.
JASCO offers high-pressure gradient and isocratic systems. The instrumentation is modular and compact so you can configure a system to a specific application. You can also combine the X-LC with any Mass Spec system with direct software control.
Click here to contact usKey Features
- X-LC systems operate up to 15,000 PSI with a range of column types.
- Up to 10 fold increase in analysis speed to save solvent and time.
- High-resolution separations using 1.5 to 2um particle size columns.
- Isocratic or high-pressure gradient binary solvent systems.
- Flow rates from 10ul/min to 10ml/min including gradient mode.
- Conventional UV or Jasco rapid response UV and fluorescence detectors.
- Detection by Mass Spec with Integrated system control.
Flexible Modular systems
The New JASCO X-LC system is completely modular so there is no need to purchase an entire system, simply choose the components required. For example, to run with any of the commercial mass spectrometers select a X-LC binary gradient pump with autosampler and column oven.
System Options
- Isocratic pump
- Binary gradient pump
- High speed autosampler
- Cooling - heating column oven
- UV-visible rapid response detector
- Fluorescence rapid response detector
- CD rapid response detector
- Computer control with EZChrom Elite
Rapid response X-LC detectors
Fluorescence Detector
JASCO is the only company with a fluorescence detector capable of handling the narrow peak widths produced by X-LC columns. The 100Hz-sampling rate is essential for working with the very narrow peak widths of only a few seconds.
Multi-wavelength UV detector
Simultaneous peak detection at 4 different wavelengths or 3 wavelengths and a 'ratio' chromatogram. Very narrow peaks are sampled at high speed, all 4 peaks can be recorded at 25 data points/sec. A special X-LC flow cell minimises peak broadening.
Circular Dichroism Chiral Detector
Designed for extreme high-pressure Liquid Chromatography applications this detector is highly selective and sensitive for chiral compounds. The X-LC CD detector provides a high speed sampling rate for CD and UV (50 data points/sec.) with simultaneous output of CD, UV and g-factor signals. A special X-LC flow cell minimises peak broadening.
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